THE LONG NON-CODING RNA XIST CONTROLS NON-SMALL CELL LUNG CANCER PROLIFERATION AND INVASION BY MODULATING MIR-186-5P

The Long Non-Coding RNA XIST Controls Non-Small Cell Lung Cancer Proliferation and Invasion by Modulating miR-186-5p

Background/Aims: Long non-coding RNAs (lncRNAs) are key players in the development and progression of human cancers.The lncRNA XIST (X-inactive specific transcript) has been shown to be upregulated in human non-small cell lung cancer (NSCLC); however, its role and molecular mechanisms in NSCLC cell progression remain unclear.Methods: qRT-PCR was co

read more

The Cholesterol-Modulating Effect of Methanol Extract of Pigeon Pea (Cajanus cajan (L.) Millsp.) Leaves on Regulating LDLR and PCSK9 Expression in HepG2 Cells

Pigeon pea (Cajanus cajan (L.) Millsp.) is a legume crop consumed as an indigenous vegetable in the human diet and a traditional medicinal plant with therapeutic properties.The current study highlights the cholesterol-modulating effect and underlying mechanisms of the methanol extract of Cajanus cajan L.leaves (MECC) in HepG2 cells.We found that ME

read more

Natural History of Pseudoboine Snakes

Even though natural history information is crucial for answering key ecological, evolutionary, and conservation questions, basic studies are still lacking 30-40mmHg for Neotropical snakes.This study aims at contributing to the knowledge of the Neotropical tribe Pseudoboini, based on literature data, analysis of museum specimens and unpublished data

read more